A striking feature of 2 Peter 2,10b-22 is the author’s multiple references to similarities and differences between humans and animals. This essay illuminates this aspect of 2 Peter 2,10b-22 by investigating comparison of humans to animals by writers older than, and (roughly) contemporary with, 2 Peter. Comparison of humans to animals is very common in the ancient world. Such comparison can be neutral, positive, or negative. 2 Peter’s comparison of humans with animals is of this last kind. Although 2 Peter’s negative comparison of humans to animals is generally similar to comparisons made by others, the specific ways 2 Peter compares them are unique.